Search results for "Charcot-Marie-Tooth disease type 2"

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Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report.

2021

Background and objectives: The aim of this study was to report a case of a patient with Charcot-Marie-Tooth disease type 2 (CMT2) treated with epigallocatechin gallate (EGCG) for 4 months in order to assess its therapeutic potential in CMT2. Materials and Methods: The study included a brother and a sister who have CMT2. The sister received 800 mg of EGCG for 4 months, while her brother received placebo for the same period of time. Both participants were assessed before and after daily administration by means of anthropometry; analysis of inflammatory and oxidation markers of interleukin-6 (IL-6) and paraoxonase 1 (PON1) in the blood sample; and motor tests: 2-min walk test (2MWT), 10-m walk…

Malemedicine.medical_specialtyepigallocatechin gallateCase ReportWalk TestDiseaseEpigallocatechin gallatePlaceboCatechinchemistry.chemical_compoundTooth diseaseCharcot-Marie-Tooth DiseaseInternal medicineMedicineHumansCharcot-Marie-Tooth disease type 2lcsh:R5-920IL-6biologyHand Strengthbusiness.industrymotor activityAryldialkylphosphataseParaoxonaseparaoxonase 1General MedicineAnthropometryPON1chemistryWalk testbiology.proteinFemalebusinesslcsh:Medicine (General)

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